A bidirectional Mendelian randomization study using genetic variants as instruments identifies five microbial taxa with ...

Genetic evidence suggests insomnia may help drive systemic inflammation, according to a study published online in Sleep. 1 ...

I am no stranger to the importance of randomization when conducting a study. I minored in psychology as an undergraduate, so I took part in the experimentation process--both by being experimented on ...

Mendelian randomization, a powerful tool in medical research, helps us understand whether certain factors truly cause disease. This technique uses genetic variations as "natural experiments" to reveal ...

Researchers argue that, in some situations where machine-learning models are used to allocate scarce resources or opportunities, randomizing decisions in a structured way may lead to fairer outcomes.

The genetic and clinical heterogeneity of breast cancer makes the identification of effective therapies challenging. We designed I-SPY 2, a phase 2, multicenter, adaptively randomized trial to screen ...

Nonrandomized observational analyses have been promoted as alternatives to randomized clinical trials. However, randomization ensures balance between groups, whereas nonrandomized studies are often ...