Artificial DNA letters beyond A, T, G, C break a fundamental pairing rule to produce nanostructures with new shapes, far greater durability, and an unexpected ability to self-sort. But the four-letter ...
Deep learning methods have demonstrated great performance for RNA secondary structure prediction. However, generalizability is a common unsolved issue on unseen out-of-distribution RNA families, which ...
Metal-mediated base pairing is an emerging paradigm in which metal ions replace or complement natural hydrogen bonds between nucleobases in DNA and RNA duplexes. By coordinating transition metals such ...